Saturday, June 26, 2010

Platelet-Rich Plasma Shows Effectiveness in Severe Achilles Tendinosis

During a presentation at the EFORT (European Ferederation of National Associations of Orthopedics and Traumatology) Congress, Dr. Raymond Monto, M.D. reported that Platelet-Rich Plasma showed effectiveness in patients with severe Achilles tendinosis who failed conventional treatments.

Dr. Monto's investigation was conducted in Madrid, Spain and focused on 27 patients who failed non-surgical treatments for 8 consecutive months. Patients' pretreatment average AOFAS (American Orthopedic Foot and Ankle Society) score was 34 and all patients had evidence of chronic tendinosis, with 9 having partial tears of the Achilles.

Using ultrasound guidance, Dr. Monto injected 4 ccs of PRP into the site of injury, then had patients fully immobilized removing stress from the Achilles for 48 hours. The most dramatic results came in AOFAS scores: 1 month after receiving PRP treatment, patients' scores increased to 84 . After 2 months, scores increased to 87. After 6 months, scores again increased to 92 with resolution of abnormalities found through MRI and ultrasound in 25 patients.

Another recent study conducted in The Netherlands concluded PRP was no more effective in treating moderate Achilles tendinosis than non-surgical, conventional methods at 12-24 week (3-6 month) follow-up. This 54 patient study was published in JAMA (Journal of the American Medical Association) at its midpoint in January, 2010.

Importantly, the difference between the two studies are: following injection Dr. Monto's patients were fully immobilized for 48 hours; Dr. Monto seemed to indicate his platelet count to an area of 2 million platelets and focused on patients with severe cases who failed conventional treatments for 8 consecutive months; The Netherlands study accepted all patients with chronic tendinosis; The Netherlands study involved more patients, yet did not indicate whether patients were immobilized or platelet concentration levels.

This is important as optimal healing has occurred when stress was removed from the injury following PRP therapy.

Dr. Monto concluded his presentation by saying, "PRP is an effective treatment for patients with severe Achillies tendinosis, with relatively no risk...there were no complications in our series...and potentially high benefits."

Reference: Monto R. Platelet-rich plasma treatment for chronic Achilles tendinosis. Paper #F264. Presented at the EFORT Congress 2010. June 2-5, 2010. Madrid.

JAMA Article review

Monday, February 15, 2010

Public Perception of Platelet-Rich Plasma

Does the use of platelet-rich plasma by professional athletes, change public perception about effectiveness and application? While hundreds of sources (including this blog) have differentiated platelet-rich plasma therapy from steroid use and blood-doping, many remain unaware of the differences. Other posts on this blog explain the different aims and means of PRP compared to illegal substances used in sport. Thus, this post contends that in the current age of professional athletics, where fans' heroes may have cheated their games, the use of PRP by athletes may create public skepticism. While this may be considered a negative result, it also serves to build awareness about PRP and encourage further public investigation. Because the true beneficiaries of platelet-rich plasma will be the working and active public, it the duty of doctors and writers to properly fill the informational gaps that exist as a result of mass-appeal reporting on this therapy.

The public knows pro athletes rely heavily on their bodies ability to perform at intensely high levels. This has conflicting implications: fans know athletes need to be healthy to perform and they know some are willing to test ethical boundaries to gain a physical advantage. For the kind of money pro athletes compete for, few are surprised that these boundaries are crossed and many people are quick to jump to uneducated conclusions about PRP.

An example of these overly quick judgments occurred in December when Tiger Woods was implicated by many bloggers and writers, to having used steroids when he received PRP injections in his surgically repaired knee. CNN's Anderson Cooper accurately distinguished between the two soon after.

It could also be argued that the public perceives treatment effectiveness favorably when athletes credit PRP for their hastened return following injury. This also has negative implications because in such cases, PRP is used simultaneously with other accepted and experimental therapies. To what degree PRP was used in relation to other therapies and recovery procedures, is not reported. There is no way of discerning to what extent PRP actually influenced the recovery in these instances.

In the last four months alone, it has been revealed John Daly, Joakim Noah, Brandon Roy, Blake Griffin and Chris Canty all received PRP for various soft-tissue injuries. In this same time period, at least five legitimate, clinical studies have been published on platelet-rich plasma, with four indicating PRP is or may be effective.

The majority of media attention surrounding PRP however, does not focus on the clinical studies. The construction worker with chronic tennis elbow is then unaware that he may be back to work sooner because he does not require surgery. The mother of four living each day in pain due to Plantars Fasciitis, is unaware she may be able to soon get on the field and play with her children. Therefore, the medical community along with writers, must continue to publish PRP clinical studies and expose them to the public, regardless of supporting or negative outcomes.

PRP has far more potential to one day save jobs and improve people's lives than it does in professional athletics. While platelet-rich plasma therapy remains in development and should currently be offered as a last resort to invasive surgery, improving the flow of accurate information will bring future accessibility and sound judgment to the use of PRP.

Wednesday, February 3, 2010

Platelet-Rich Plasma Injection More Effective than Cortisone Injection

A recently published study by Dr. Taco Gosens from the Netherlands, revealed platelet-rich plasma (PRP) injections were more effective than cortisone injections for chronic tennis elbow. The controlled trial studied 100 patients with chronic lateral epicondylitis (tennis elbow). The results are reported in this month's (Feb.) Academy Journal of Sports Medicine.

Patients were randomly selected into either the PRP group or corticosteroid group. Successful treatment was defined as "more than 25% reduction in visual analog score or DASH score without a re-intervention after 1 year."

At one-year follow-up, 73% of patients in the platelet-rich plasma group were treated successfully compared with just 51% of the cortisone group. What was further significant: the corticosteroid group was initially better and then declined, whereas the PRP group improved steadily.

In conclusion, the study reported treatment of chronic lateral epicondylitis with PRP reduces pain and significantly increases function. PRP significantly exceeds the effect of corticosteroid injection for the same injury.

Currently, PRP remains a therapy for patients who have failed other non-surgical treatments. As cortisone injections are temporary pain relievers and can cause tissue damage, they have also been a final resort when other non-surgical therapies fail.

Based on this study, PRP could eventually be used as a substitute for cortisone injections. PRP is shown to be more effective and has the advantage of using patients' own natural components to heal soft-tissue tears. Cortisone as an outside agent introduced to the body, is designed to temporarily relieve pain, but can be further damaging to an injury. As evidence supporting PRP effectiveness continues to be published and insurance companies come to understand PRP's value, the substitution is likely.

View Abstract.

Monday, January 25, 2010

Platelet-Rich Plasma Arthritis Video

Susan Chamblee had tried just about everything to fix her extremely painful, arthritic knees. With her final option being total knee replacements, requiring a long, painstaking recovery and the added expense of surgery, she discovered platelet-rich plasma therapy (PRP) and opted to try it.

While PRP is in its infancy in development and has had both effective and ineffective research results, this video illustrates why PRP should be used in cases such as Ms. Chamblee's.

Watch this Video


Note: Ms. Chamblee was in no way compensated for her story and testimony.

Thursday, January 21, 2010

Platelet-Rich Plasma and Arthritis

A recently published PRP study from the Rizzoli Orthopedic Institute in Bologna, Italy, found platelet-rich plasma (PRP) injected in knees with degenerative cartilage lesions (arthritis), can improve knee function.

The study, published in October 2009 by Kon et al, consisted of 100 patients and 115 knees affected by chronic degeneration. 150-ml of venous blood was twice centrifuge. 3 PRP units of 5-ml each were for the intra-articular injections. Patients were evaluated clinically at the beginning and the end of the treatment and at both 6 and 12 months following treatment. IKDC, objective and subjective, and EQ and VAS were used for clinical evaluation. Importance of sex, age, BMI and grade of OA was evaluated statistically.

The statistical results show steady improvement up to 6 months following treatment. The results at the 12 month follow-up were significantly worse, although higher than the basal level.

These results indicate intra-articular PRP knee injections produce favorable results on degenerative cartilage lesions.

Click here for summary of study.

Tuesday, January 19, 2010

Recent JAMA Platelet Rich Plasma article

A new PRP study from researchers in the Netherlands declared platelet-rich plasma is ineffective in healing moderate Achilles tendinopathy. Researchers had 54 patients gauge pain levels at 6, 12 and 24 weeks following treatment. One patient group was given a PRP injection and the other, a saline injection (placebo). The study published in JAMA (Journal of the American Medical Association) by de Vos et al, concluded PRP was no more effective than the saline injection when both groups added therapeutic exercises into their recovery routines.

The study has received extensive media coverage and has been quick to cite PRP as ineffective. It is important to view the controls of the study before conclusions are made however.

This study's data does support PRP's ineffectiveness after a 6 month period in only moderate Achilles tendinopathy. It does not include either minor or severe cases. This study was published at its midpoint. Researchers will follow up on patients' recovery in 12 months and it is possible PRP patients will continue to improve and the placebo group will not.

Importantly, no data is available on platelet concentrations given to the PRP group. As this study is one of many to come determining the proper use of PRP, platelet concentration levels in PRP groups will be crucial to disclose. If patients received too low a platelet concentration in their injection, results would likely vary in higher doses. This will be a vital component of determining the optimal formula of PRP.

Patients receiving PRP to treat plantar fasciitis and Achilles tendinopathy have been benefited by the use of a boot following therapy. This allows the injury time to heal without chronic tension and permits the growth factors to work without continued trauma. There is no data in this study on whether boots were used.

Legitimate studies are very important to further the understanding of PRP's effectiveness and uses and this study should be recognized as such. The study is however, incomplete. This must be taken into account before significant conclusions are drawn about PRP's effectiveness.

Thursday, January 14, 2010

Regenerative Medicine in US and China

Regenerative Medicine is a developing interdisciplinary field of research and clinical applications aimed at repairing, replacing or regenerating cells, tissues, or organs. Regenerative Medicine uses a combination of approaches including gene therapy, stem cell transplantation, tissue engineering, and the reprogramming of cell and tissue types.

An article in this month's Regenerative Medicine Journal states, "China has been able to catapult itself into the forefront of regenerative medicine" (Thorsteinsdóttir et al). While Chinese investment in stem cell research has increased by over US$40 billion in the past 14 years, and has increased its peer-reviewed publishing from 37 in 2000 to 1,116 in 2008, the emergence is in large part due to the lack of regulation.

According to the Toronto Sun, there are over 200 cases of clinics and hospitals offering completely unproven stem cell therapies for profit, greatly tainting China's emergence.

Meanwhile, while the founding of US-based biotech companies has slowed due to the high-price of research and development and FDA regulation, the United States has awarded generous grants to to Universities and research teams in Michigan and California to help economic development through regenerative medical innovation.

Wednesday, January 6, 2010

Scaffold Tissue Engineering in Regenerative Medicine

The November issue of Discover Magazine contained an article about new attempts to create implants that simulate connective tissue through scaffold tissue engineering.

Tendons are difficult to repair once severed due to the challenge of reconnecting them to bone. Surgical attempts to anchor the severed tendon to bone often fail because the materials are very different.

Stavros Thomopoulos and Younan Xia, biomedical engineers at Washington University in St. Louis, "are building synthetic interfaces that re-create the architecture of natural connective tissue in hopes of tricking the body to regrow the broken connection."

The scaffold made of microscopic nanofibers, is dense and bonelike on one end and pliable and tendonlike on the other, increasing the likelihood for a successful connection.

These new interfaces are an encouraging development in Orthopedic regenerative medicine.

Read Full article here.

Monday, January 4, 2010

Platelet Rich Plasma Potential

OrthoSuperSite.com is the website of a top healthcare business publication titled Orthopedics. In 2009, Medical Marketing & Media (MM&M), a business publication for healthcare marketers, recognized Orthopedics as a finalist for “Best Healthcare Business Publication.” OrthoSuper Site.com publishes daily information about all orthopedic topics. A December 22 article from OthoSuperSite revealed their most viewed article in 2009 transcribbed a clinical round table discussion on the role of platelet-rich plasma in connective tissue repair.

This is reflective of both public and industrial interest in the emerging therapy's potential.

Friday, January 1, 2010

Tuesday, December 29, 2009

Differentiating "Blood Doping" and "Blood Spinning"

Platelet-Rich Plasma Therapy (PRP) has begun to adopt the appropriate title of "blood spinning." This post aims to differentiate that label from "blood doping," a separate treatment performed for a completely different purpose. While a blood transufussion means of doping relies on an athlete's blood being spun in a centrifuge similar to PRP, the materials being extracted from the centrifuge are different in both procedures, with seperate uses and intentions. Simply stated, PRP aims to repair soft-tissue tears naturally, blood doping attempts to enhance red blood cell counts artificially.

PRP is the removal of a small amount of blood from a patient with a soft tissue injury (tendon, ligament, muscle, etc.). The blood contains healing components called platelets that release growth factors used by the body to grow and create cells. These platelets are not normally used by the body in large enough concentrations in such injuries. Patients' blood is thus spun in a centrifuge, which extracts these natural platelets. The platelets are then concentrated in a specific dose and injected directly into the injury, catalyzing the body's natural healing abilities. This entire process takes roughly an hour.

If you were trying to fuse a split 2 x 4 with a small drop of wood glue, it may stick momentarily, but when used, it would be unstable and likely break again. PRP gives the woodworker the entire bottle of wood glue to fuse the split wood. The process is very safe with almost no risk of side effects because the platelets are natural and come from the patient. The World Anti-Doping Agency (WADA) has approved the use of PRP in all soft tissue excluding intramuscular injection. When injected directly into muscle, it is possible PRP can enhance growth, thus creating a similar outcome to steroid use.

PRP has been widely used in professional athletics and deemed a legal form of therapy for soft tissue tears and tendinitis but the therapies true potential lies in healing injuries for the weekend warrior and the construction worker with a torn elbow tendon.

"Blood Doping" of the other hand has various means and a multitude of procedures, all with the same intention: to increase red blood cells in the blood stream. It has been deemed illegal by WADA, the International Olympic Committee and International Cyclist Union and can have life threatening side effects. Red blood cells carry oxygen to muscles and increases red blood cell count resulting in oxygen being taken to muscles more efficiently. This gives aerobic athletes a significant advantage over competition as they battle less fatigue.

While red cell counts can be increased naturally by training at high altitudes where less oxygen is present, blood doping gives athletes an increased and illegal boost. To gain the higher count through doping, athletes inject themselves with erythropoietin (EPO), a hormone that stimulates red blood cell production. EPO has been pervasive in the top levels of cycling for the past two decades. Because it thickens the blood, it has dangerous side effects such as blood clotting that can cause heart attacks and strokes. An abnormally high red blood cell count can also result in impaired blood flow and death.

Athletes can also have four units of blood removed a month prior to competition and spun through a centrifuge to remove the red cells. Three weeks later, the concentrated red blood cells are transfused back into the athlete. Thus, the blood spinning is inherent to this process but the material being collected is unique and for a different purpose.

If PRP is the wood glue that reconnects the severed 2 x 4 making it once again useful, blood doping is taking a pristine 2 x 4 and infusing it with graphite for artificial strengthening.

Where PRP is described as "blood spinning" it should not be confused with or categorized as "blood doping."

Monday, December 28, 2009

CNN's Platelet Rich Plasma and Tiger Woods Segment

Anderson Cooper and Dr. Sanjay Gupta explained PRP and the treatment of Tiger Woods on AC360 on December 17. The PRP segment is informative and easy to understand. Cooper and Dr. Gupta discuss Dr. Anthony Galea use of PRP in Woods' knee following surgery. Although Dr. Galea has been arrested for distribution of Human Growth Hormone in the US, there has been no indication Tiger had any association with this practice.

While PRP is "blood spinning," it should not be confused with "blood doping." This segment distinguishes blood spinning as acceptable and beneficial practice.

Wednesday, December 16, 2009

Monday, December 7, 2009

Ultrasound's Importance in Measuring Platelet-Rich Plasma Therapy Results

In a European PRP study using horses as test subjects, utilizing ultrasound to measure healing levels proved to be very useful. Ultrasound uncovered the improvement in tissue alignment during healing with PRP as opposed to placebo. Ultrasound also confined the healing course is more efficient using PRP (Bosch et al).

Excerpt from Study:

"The effectiveness of new therapies to treat tendon injuries is difficult to determine and is often based on semi-quantitative methods, such as grey level analysis of ultrasonographic images or subjective pain scores. The alternatives are costly and long-lasting end-stage studies using experimental animals. In this study, a method of ultrasonographic tissue characterisation (UTC), using mathematical analysis of contiguous transverse ultrasonographic images, was used for intra-vital monitoring of the healing trajectory of standardised tendon lesions treated with platelet rich plasma (PRP) or placebo. Using UTC it was possible to detect significant differences between the groups in the various phases of repair. At end stage, over 80% of pixels showed correct alignment in the PRP group, compared with just over 60% in the placebo group (P<0.05). UTC also showed significant differences in the course of the healing process between PRP treated and placebo treated animals throughout the experiment. It was concluded that computerised analysis of ultrasonographic images is an excellent tool for objective longitudinal monitoring of the effects of treatments for superficial digital flexor tendon lesions in horses."



Researchers: Bosch G, René van Weeren P, Barneveld A, van Schie HT.

Article Title: "Computerised analysis of standardised ultrasonographic images to monitor the repair of surgically created core lesions in equine superficial digital flexor tendons following treatment with intratendinous platelet rich plasma or placebo"

Location and Publisher: Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.

Date Published: 2009, Nov 19

Implant Dentistry Reports Platelet-Rich Plasma Enhances Bone and Tissue Growth

At the American Academy of Implant Dentistry prominent researcher and Journal of Oral Implantology editor, James Rutkowski, DMD, PhD, reported the potential for accelerated healing of dental implants using platelet-rich plasma. While this is not an orthopedic study, Dr. Rutkowski noted its continued success in sports injuries and orthopedics.

Dr. Rutkowski said about PRP in dental implants, "...PRP treatments can jump start bone growth and implant adherence in just two weeks...Accelerated healing is a goal we've been seeking in implant dentistry and we now have treatment that activates the natural healing process. It is a very promising development..."

He estimated 10 percent of implant dentists have used PRP and that number will continue to rise.

It seems increasingly numbers of prominent doctors believe PRP is effective and that trend will continue.

Monday, November 23, 2009

Bob Kurtz's PRP Testimony

A Video Testimonial from former CNN sportscaster, current pastor and Guinness Book World Record holder for most consecutive golf holes played.

Thursday, November 19, 2009

Revolutionary Tendonitis Treatment Leads to Amazing Guiness Book World Record

At 68 years old, Pastor Bob Kurtz of Cullman, Alabama, beat his own world record in June by playing 500 consecutive holes of golf, an astounding feat that was aided by a revolutionary new tendonitis treatment called Platelet-Rich Plasma (PRP).

A group from Pastor Bob’s congregation at St. John’s Protestant Evangelical Church devised the concept of a golf marathon to raise money for children in Kenya. An avid golfer who spent his free time devoted to the development of his golf game, Pastor Bob was asked to be the “iron man” of the marathon as he does not have the typical background of your average pastor.

He began his career in broadcast journalism and twenty years later, at 45, was the top sportscaster for CNN. But his position lacked a spiritual connection. Kurtz believed the industry was too material-centric revolving around money, power, and egos. Following in his father Chuck Kurtz’s footsteps, Bob turned to the ministry. He devoted his energy to serving God and others as a pastor for more than 20 years. Then it was decided that Mr. Kurtz would become the ultimate golf iron man.

A standard golf marathon consists of 100 holes, but Kurtz’s love for golf and his philanthropic energy wouldn’t settle for the status quo. He completed three marathons of 168 holes and 220 holes, and, in 2008, broke the 401 hole Guinness Book World Record by playing 405 consecutive holes of golf.

“Then I thought I could do 500,” says Kurtz. “I had a year to get ready and I was ready except for one problem, and that was a torn tendon in my right elbow. That was a major concern.”

Kurtz had been hitting hundreds of golf balls per day to prepare for the ultimate marathon accomplishment and in his conditioning, acquired what is known as the golfer’s elbow: a soft-tissue tendon tear on the inside of his right elbow.

“I was physically strong enough to hit that many golf balls but was growing more and more concerned about the right elbow, the golfer’s elbow,” Kurtz continued. “It’s very, very painful.”

With the 500 hole marathon approaching, and an increasingly painful tendon tear, Kurtz sought help at Alabama Spine and Joint Center in Birmingham. With surgery requiring excessive recovery time and strength loss, Kurtz needed a medical treatment that could expedite the healing process and discovered Platelet-Rich Plasma Therapy (PRP).

“Mr. Kurtz opted for PRP, a developing treatment that has gained prominence for its potential to heal soft-tissue injuries, such as tennis elbow, golfer’s elbow, Achilles and knee tendonitis, quickly” says Dr. Kenneth A. Jaffe, an Orthopedic surgeon at ASJC. “It is very safe and there is almost no risk of complication or side effects. Due to its infancy in research though, it is still considered somewhat experimental.”

Mr. Kurtz’s treatment was a very simple, straightforward procedure to perform. PRP requires about an hour and involves removing a small amount of a patient’s blood and then rapidly spinning it in a centrifuge or filtration system. Healing components of the blood known as platelets are separated from red blood cells and re-injected directly into the injured area, where blood would rarely go otherwise. The platelets are naturally occurring, and normally used by the body in smaller doses. This procedure can catalyze the body’s natural healing response and uses a highly concentrated dose, from 3 to 10 times that of normal blood, of platelets.

“The healing components used by PRP are autologous, meaning they come from the patient’s own body. PRP injections are very safe and there is almost no risk of rejection,” says Dr. Jaffe. “The question is to what extent the injection will heal the injury.”

While a multitude of clinical studies are underway, the research to this point has concluded PRP can be beneficial and warrants further research. PRP has been used for over 20 years in the dental community and is finally making its way into the treatment of sports injuries and tendonitis. An October review in the prestigious Journal of American Academy of Orthopedic Medicine concluded the treatment continues to show promise and more research is needed to prove its full effectiveness.

“PRP tendon treatment is new and I believe patients should be well informed when facing treatment options,” said Dr. Jaffe. “Mr. Kurtz needed his body to perform at a high-level and was willing to be on the leading edge of this treatment for its sake.”

Many other athletes who also require frequent peak performances have turned to PRP. Hines Ward of the Pittsburgh Steelers credits his 2009 Super Bowl success to PRP. Ward became injured in the first quarter of a playoff game with a sprain to the medial lateral ligament in his right knee. Ward received PRP the following day. In the Super Bowl, two weeks later, Ward caught two passes in the Steelers victory over the Arizona Cardinals.

In a New York Times article, Ward stated, “I think it really helped me. The injury that I had was a severe injury, maybe a four- or six-week injury. In order for me to go out there and play in two weeks, I don’t think anyone with a grade-2 M.C.L. sprain gets back that fast.”

Many athletes have also successfully treated their injury and expedited their recovery, including Ward’s teammate Troy Palamalu, New York Giants Chris Canty, LA Dodgers pitcher Taiko Saito, PGA Tour golfer John Daly and recently, 2009 NBA draft, number-one selection Blake Griffin.

“It is not just professional athletes who may benefit from PRP,” Dr. Jaffe says, “the recreational athlete and elderly alike can have their injuries treated. It may eliminate the necessity for certain individuals to receive surgery as their only corrective means. It’s significantly cheaper and less painstaking than soft-tissue repair surgery.”

Mr. Kurtz agrees. “It wasn’t difficult at all. It’s kind of interesting because you can sit there and watch what they’re doing. It turned out to reduce a lot of the pain and gave me my confidence back. In all honesty, I never thought about it (the injury) the two days of the marathon.”

Following PRP, Mr. Kurtz completed the 500 hole marathon in June, by playing for two days and one night. When he completed his 500th hole, blowing away his previously held record of 405 holes, he had raised over $40,000 for children’s charities. The energetic and ambitious Mr. Kurtz was very thankful for the option of receiving PRP.

“This injection helped me out enormously. It exceeded my hopes.” Kurtz then chuckled, “We finished with the 500th hole and the last thing I thought about was an aching elbow. There were a lot of other things that ached, but not the elbow.”

Monday, November 9, 2009

Platelet Rich Plasma and Athlete Healing

The Chicago Daily Herald published an article about the potential benefits of Platelet Rich Plasma. The 11/9 article cites Eric Hedstrom, a Purdue offensive lineman, who has battled constant injury through his college career. Hedstrom missed the majority of last season with a shoulder blowout that required surgery. Following the initial surgery, it took Eric 3 months before he was able to remove his arm from the sling.

On the opening day of practice this season, Hedstrom re-injured the shoulder and was faced with the same situation from the previous season. This season however, he had a new treatment option: Platelet Rich Plasma.

Hedstrom opted for the therapy under the guidance of the Chicago Bulls and White Sox team doctor, Dr. Romeo. Since having Platelet Rich Plasma injected into his injury, Hedstrom has seen promising results. "So far," he says, "its healing a lot faster and a lot better." His arm is out of the sling and being strengthened after a month.

The article notes that it is not just high-level athletes Platelet Rich Plasma might benefit. The Therapy may benefit everyone from high school track runners to the elderly.

The mother of an injured high school athlete who received PRP in a bone injury and recovered, had this to say about those debating whether to receive the therapy: "I would say defenitely get it. Because its not going to hurt you, but there's always the possibility that it could help you."

To read the full article, click here.

Monday, November 2, 2009

The Doctors of Platelet-Rich Plasma Therapy

As an Orthopedic Surgeon, I help patients prevent and correct disorders of the skeletal system, muscles, joints and ligaments. I recently read an article about Platelet-Rich Plasma Therapy written by a neurologist who markets the general benefits of PRP. It is of concern that when doctors work outside of their area of expertise, they oftentimes make exaggerated claims for financial gain. Patients need to be mindful of the motives when seeking PRP Therapy in the community. It seems PRP advertisements can be disguised as a legitimate clinical documents from reliable sources.

Platelet-Rich Plasma Treatment simply stated is an injection of a concentrated dose of blood platelets into a soft tissue injury to catalyze the body's natural healing response and expedite recovery. These soft tissue injuries in which PRP has been shown to be effective, include tendons, ligaments, joints and muscles. The soft-tissue injury is treated by Orthopedic surgeons as Orthopedics is defined by MedicineNet.com as: "the branch of medicine that deals with the prevention or correction of injuries or disorders of the skeletal system and associated muscle, joints, and ligaments."

It is my contention that patients with injuries which could be potentially aided by PRP Therapy should consult physicians who specialize in treating those injuries: the Orthopedic Community, and not any doctor willing to administer PRP Therapy for monetary compensation. While research and clinical data show Platelet-Rich Plasma Therapy is very safe and has tremendous potential as an alternative to invasive soft-tissue surgical repair of the musculoskeletal system, it is important that the patient and treating physician know the facts behind the therapy when deciding if it is right for their injury. The question to be addressed is what is the probability that it will work for each condition? It is the understanding of when to use PRP or surgery that makes the orthopaedist a valuable resources to the patient.

The origins of PRP Therapy research for musculoskeletal conditions comes from the Orthopedic community. As this is our area of expertise, it is our community that should be handling PRP Therapy consultations. Patients interested in the receiving PRP treatment for musculoskeletal conditions should not be mislead into taking it from anyone outside the Orthopedic community. The Orthopaedist is an expert in the diagnosis and treatment of injuries with invasive or non invasive techniques. Doctors practicing hybridized medical specificity, such as "neuro-orthopedics," and looking to administer PRP Therapy, should be called into question, not for an appointment.

Saturday, October 31, 2009

Platelet Rich Plasma in Joint Injuries and Osteoarthritis

Arthritis specialists predict by the year 2030 there will be 67 million Americas with arthritis and Platelet-Rich Plasma injections may alleviate if not eliminate the pain arthritis will cause. An article in the Boston Globe centers around Josephine "Jo" Foster, a 79 year old Massachusetts restaurant hostess plagued by osteoarthritis in her knees, who opted for PRP injections as treatment.

"I haven't got time for arthritis," says Foster in the article. "That's old people, not me."

Disease trackers warn the number of young Americans with painful osteoarthritis will increase due to obesity as time elapses.

“It’s not at all uncommon to see severe osteoarthritis in people at age 40 because of the presence of obesity," says the Arthritis Foundation's chief science officer, Dr. John Harden said.

But for Jo, knee replacement surgery was not an option. She had both knees injected with PRP in September.

“My doctor said there may be pain so I went home and waited for the pain,’’ said Foster, who has undergone a variety of other noninvasive therapies unsuccessfully.

“There is no pain now,’’ Foster continued. “None whatsoever.’’

Foster’s physician, Dr. Joanne Borg-Stein, specializes in rehabilitation and sports medicine. Dr. Borg-Stein has treated about 175 patients with Platelet-Rich Plasma injections in the past year.

“I like to be honest with patients and tell them that we are just starting to get data in from animal trials, that we don’t have really good human data,’’ Borg-Stein said. “People have to be willing to accept that they are on the leading edge with this.’’

To read this Boston Globe article, click here and scroll down to "Boston Globe: What a Pain"